What major body of water is located between Saudi Arabia and Africa?

The Red Sea is the major body of water located between Saudi Arabia and Africa. It serves as a crucial maritime route, connecting the Mediterranean Sea to the Indian Ocean via the Suez Canal. The Red Sea is known for its unique marine biodiversity and is a significant area for trade and transportation.

The Mediterranean Sea is situated to the north of the Red Sea and separates Europe from Africa, while the Black Sea is located far to the north of the Mediterranean, bordered by Europe and Asia. The Aegean Sea lies between Greece and Turkey and is not relevant to the geography of Saudi Arabia or Africa. The Red Sea's strategic importance and distinctive geographic positioning make it the correct choice for this question.